Genetics

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Your genes are the instructions for making you. They help make you unique—similar to all life on Earth!

Inside the cells of every living thing are molecules of DNA. Hidden within DNA's structure is a universal language: the genetic code.

This simple but incredibly versatile code spells out genes for various traits. Humans have been hacking into this code for thousands of years.

At first, they did it by breeding plants and animals with useful traits, a process called artificial selection. Genetic engineering technology makes it possible to edit the code directly.

Click "the image" to find out how genes affect our lives!


 

Genetics

So far, you know what DNA is and does in the body. Now you will learn more about what DNA has to do with your appearance.

In your science journal, answer these questions.

1.  Do you know how DNA is passed from parents to offspring?

2.  How do you think cells determine which genes offspring get? 

3.  How are you similar to your parents?

4.  Can you think of some traits that were passed down from your biological parents to you? If so, what are they? If unsure, name some traits you think would be passed down from parents to children.

 

 

Genetics is the science of genes and heredity. Our bodies are made up of tiny, microscopic cells. Each cell has a nucleus that contains 46 chromosomes. Each chromosome has hundreds to thousands of genes that describe everything about you! Your hair color, height, eye color, allergies, and overall health are already decided for you and encoded in your genes! This special code is referred to as the genetic code. Heredity explains how these traits or characteristics are passed from parents to offspring (children). Let's explore more about how this works!

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Inheritance

Your genes make you unique. Everyone has genes for eyes, ears, skin, bones, fingers, and toes. The combination of the genes you get from your biological parents gives you a unique appearance, including eye color, hair color, skin color, and nose and face shape.

Gene Alleles

You have learned that DNA is wound into chromosomes. Each chromosome has a gene made from a specific section of DNA for a specific trait. You can see in the image the small sections on each chromosome that determine the specific trait.

All humans have 23 pairs of chromosomes. One half of the pair comes from your biological mom and the other half from your biological dad. Each chromosome has a copy of the same gene, but there are two versions. The different versions of the same gene are called alleles. Each biological parent donates one allele for each gene to an offspring.

There are two types of alleles:

For example, if you get dominant brown eye color alleles from your biological parents, you will have brown eyes. You will also have brown eyes if you get one dominant brown eye color allele from your biological mother and one recessive blue eye color allele from your biological father. But if you receive both parents' recessive blue eye color alleles, you will have blue eyes.

Alleles are usually noted by letters of the alphabet; recessive alleles are lowercase letters, and dominant alleles are the capital versions of the same letters. For example, the allele for blue eyes (a recessive trait) might be represented by "b," while the allele for brown eyes (a dominant trait) might be "B."

Below is an image of a chart showing options of a child's genes based on whether the parents have blue or brown eyes.

Genotype chart

 

The two alleles describing a single trait of an organism are called its genotype. For instance, a brown-eyed person can have a Bb or a BB genotype, while a blue-eyed person has a bb genotype.

There are two ways to describe genotypes:

·      Homozygous: the two alleles are the same, either dominant or recessive

·      Heterozygous: the two alleles are different, one dominant and one recessive

You cannot easily see people's alleles, so it is hard to know their genotypes. A brown-eyed person could have a genotype of BB or Bb.

The physical expression of a genotype is called a phenotype. You can often tell a person's phenotype just by looking. It is easy to see that a person has brown or blue eyes.

Below is an image of two eyes, one blue and one brown, with differing genotypes.

Eye Color

 

You might wonder how there can be more than two eye colors. Instead of just blue or brown eyes, people can have green, hazel, grey, or even amber eyes. How can this happen with only two alleles?

The answer is that more than one gene decides eye color. Many genes are involved in traits with various phenotypes, such as hair color, skin color, and height.

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Genetic Variance

You've learned how traits are passed down from biological parents to offspring. So far, you have seen how simple dominance works when a dominant allele completely masks a recessive allele.

In your science journal, answer these questions.

1.  Do you think all traits happen because of simple dominance? Why or why not?

2.  Can you think of a trait that has different phenotypes? 

Simple Dominance

        Who introduced the world to genetics?

Almost 200 years ago, a monk named Gregor Mendel studied pea plants to learn how heredity works. Pea plants, like people, have chromosomes and produce offspring with two parents through sexual reproduction.

Greg Mendel

 

Gregor Mendel started the science of heredity, or inheritance, and helped explain why offspring from sexual reproduction sometimes look like their parents and sometimes do not.

 

Mendel's work with pea plants helped people understand how traits are inherited. But other plants and most animals are more complicated than pea plants.

Flower petal color is an example of a trait with many different phenotypes. In the picture, neither the red allele (CR) nor the white color allele (CW) is dominant. When the two alleles mix, they make a new phenotype—pink (CRCW). This is incomplete dominance.

Incomplete Dominance

 

Codominance works similarly. As with incomplete dominance, there is no dominant phenotype. Instead, both traits show up when codominant alleles mix. In the picture, a roan cow (CRCW) has both red and white hair, getting its red hair from one parent (CRCR) and its white hair from the other parent (CWCW).

Can you tell the difference between simple dominance, incomplete dominance, and codominance?

Codominance

 


 

Punnett Squares

 

A Punnett square is a tool biologists use to see how parents pass different traits to offspring.

You can predict the traits of pea offspring by making Punnett squares of the alleles of parent plants.

Remember:

Science Journal

Look at the example of a Punnett square that crosses a green plant with two green color alleles (GG) and a green plant with both green and yellow color alleles (Gg).

In your science journal, answer the questions:

1.  How many of the new plants will be GG?

2.  How many of the new plants will be Gg?

3.  How many of the new plants will be green?

 


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